Anticonvulsants such as gabapentin (Neurontin), levetiracetam (Keppra), pregabalin (Lyrica), phenytoin (Dilantin), and topiramate (Topamax).Antidepressants such as amitriptyline (Elavil), duloxetine (Cymbalta), escitalopram (Lexapro), imipramine (Tofranil), fluoxetine (Prozac), nortriptyline (Aventyl, Pamelor), paroxetine (Paxil), sertraline (Zoloft), and venlafaxine (Effexor).Side effects for antidepressants and anticonvulsants include anxiety, restlessness, drowsiness, dry mouth, and weight gain anesthetics can cause dizziness, drowsiness, and nausea. Pain Relief: Neuropathic and Nerve-Blocking Medicationsįor neck pain caused by a pinched nerve or nerve disorder, relief may come from antidepressants, anticonvulsants, and nerve blockers - medications that work by interfering with the way that the brain receives or interprets pain signals or by blocking the pain signals being sent from an irritated nerve. Some are habit-forming and cause side effects, like drowsiness, dizziness, and confusion, which can prevent you from thinking clearly and safely driving a car or operating machinery. Food and Drug Administration, muscle relaxants lose their effectiveness after about two weeks. These medications help relieve neck pain caused by muscle spasms and are most appropriate for short-term use. Side effects include drowsiness, dizziness, and nausea. Dosing must be carefully monitored because the body can develop a strong physical dependence on them over time. Some of the medications in this category are combination drugs that include acetaminophen or aspirin, which also has anti-inflammatory properties. Opioids work by interfering with the brain's normal processing of pain signals. However, side effects include gastric bleeding, stomach pain, longer time for blood clotting if you are bleeding, hypertension, and fluid retention.Īn opioid may be prescribed for more severe neck pain that can't be controlled using acetaminophen or NSAIDs alone. Nonsteroidal anti-inflammatory drugs, or NSAIDs, like ibuprofen (such as Advil) and naproxen (such as Aleve) relieve pain and reduce swelling by inhibiting the body's inflammatory response.Acetaminophen (such as Tylenol) is effective as a pain reliever, but will not improve inflammation, the source of neck pain due to conditions like arthritis of the joints of the vertebrae.They are effective against neck pain caused by muscle and joint problems, such as muscle strains or osteoarthritis. These over-the-counter medications are considered the first line of attack for most neck pain. For example, a drug designed to treat neck pain caused by a pinched nerve may not work for pain from a muscle spasm or inflammation. There are many different drugs available, and which one to use will depend on the source of your neck pain. Along with rest and physical therapy, medication is often one of the first ways to treat neck pain.
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